https://doi.org/10.15255/KUI.2020.045
Published: Kem. Ind. 69 (9-10) (2020) 541–555
Paper reference number: KUI-45/2020
Paper type: Review
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Contribution to the Research of Glucosinolates (2005–2020): Structural Diversity, Degradation, and Biological Potential

I. Blažević

Abstract

This review paper presents a contribution to the research of glucosinolates over the period 2005–2020, which was obtained during work at the Faculty of Chemical Technology, University of Split. After review of the comprehensive documentation, it was determined that a significant number of proposed structures lack important structural information that would be provided by NMR and MS spectroscopy, and today the number of glucosinolates is still variable. In the recent study of Hesperis genus, 4-O-D-apiosylglucomatronalin was identified, which gives the total number of glucosinolates today ranging from 89 to 136 structures. In order to identify the sources of specific glucosinolates that could act as precursors of biologically active isothiocyanates, the content of glucosinolates in plants was investigated. The study also includes the degradation of glucosinolates (enzymatic, thermal, and chemical), as well as biological activity (cytotoxic, antimicrobial, anti-inflammatory, etc.).

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Keywords

glucosinolates, degradation, isothiocyanates, biological activity