https://doi.org/10.15255/KUI.2019.040
Published: Kem. Ind. 68 (9-10) (2019) 477–485
Paper reference number: KUI-40/2019
Paper type: Review
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Application of Tubular Meso- and Micro-reactors in Organic Synthesis and Photochemistry – Go With the Flow!

K. Pavlović, A. Ratković, M. Gojun, A. Šalić, B. Zelić and I. Škorić

Abstract

In organic chemistry, more attention is paid to syntheses in micro- and meso-flow systems, which has a number of advantages over batch synthesis. The main advantages of the implementation of organic synthesis in flow reactors are greater efficiency, ecological acceptability and safety. Despite this, the chemistry of flow systems cannot be used as a universal approach for all problems that can be considered by organic synthetic chemists, and prior to the implementation of selected reactions, it is worth considering the cost-effectiveness of batch synthesis. The safety and environmental eligibility of synthesis in flow reactors significantly contributes to the use of a small volume of chemicals and solvents, since the reactions are carried out in micro- or mezo-reactors made, usually, from inert materials. Due to the numerous advantages of organic reactions in flow systems, they are under continuous research. The reaction conditions are optimised in order to increase the efficiency and safety of processes and their magnification.

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Keywords

photochemistry, organic synthesis, micro-reactors, application of flow reactors, flow systems