https://doi.org/10.15255/KUI.2019.030
Published: Kem. Ind. 68 (9-10) (2019) 457–468
Paper reference number: KUI-30/2019
Paper type: Review
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Preparation of 3D Porous Scaffolds for Bone Tissue Engineering

M. Ivanković, L. Bauer, A. Ressler, A. Rogina, M. Antunović and H. Ivanković

Abstract

Bone tissue engineering (BTE) is a fast growing field focused on the development of bioactive 3D porous scaffolds as temporary extracellular matrixes that support cell attachment, proliferation and differentiation, and stimulate bone tissue formation in vivo. Over more than ten years, our group has been devoted to developing new biomaterials and methods to prepare 3D porous scaffolds for BTE applications. The potential of natural porous structures such as marine skeletons, composite materials, and hydrogels based on biodegradable polymers and bioresorbable hydroxyapatite ceramics have been studied. In this paper, an overview of our research and main achievements, published in international scientific publications, is provided.

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Keywords

bone tissue engineering, 3D scaffolds, porous structure, cuttlefish bone, hydroxyapatite, biodegradable polymers, hydrogels