https://doi.org/10.15255/KUI.2025.017
Published: Kem. Ind. 75 (1-2) (2026) 91–101
Paper reference number: KUI-17/2025
Paper type: Review
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Therapeutic Bioactives in Medicinal and Edible Plants for Hyperuricemia Treatment

J. Jumardi

Abstract

Hyperuricemia, a widespread metabolic disorder, is marked by abnormally high blood uric acid concentrations. This condition arises primarily from either excessive uric acid synthesis, impaired renal excretion, or a combination of both. Beyond its well-established link to gout, hyperuricemia is also a contributing factor to various other health complications. While conventional pharmacological treatments offer therapeutic benefits, their adverse side effects pose potential risks to patients. This review explores common medicinal and edible plants with demonstrated uric acid-lowering properties, emphasising their active constituents. These bioactive agents function through multiple mechanisms, such as suppressing uric acid synthesis, enhancing renal excretion, and reducing inflammatory responses. By evaluating the therapeutic potential of these plant-based compounds, this study aims to provide valuable insights into alternative strategies for hyperuricemia treatment.

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Keywords

anti-gout, antioxidant, anti-inflammatory, uric acid, xanthine oxidase