Functional State Modelling Approach for Batch Cultivation of Saccharomyces cerevisiae

I. Hristozov, T. Pencheva, S. Tzonkov and B. Hitzmann

Abstract
An application of functional state modelling approach for aerobic batch baker’s yeast cultivation is presented in this paper. The functional state approach is appropriate for description, monitoring and control of complex processes such as bioprocesses. The main idea is to divide the process into macrostates, called functional states, according to behavioural equivalence. In each functional state the process is described by a conventional type of model, called a local model, which is valid in this functional state only. Functional state modelling approach is more convenient than using of a global model when parameter estimation should be made. The main advantage of functional state modelling approach is that the parameters of each local model can be separately estimated from the parameters of the other local models. The concept of functional state modelling approach is applied for real aerobic batch baker’s yeast cultivation.

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Keywords
batch process, modelling, functional states