Exploring the Role of Poly (N-vinyl pyrrolidone) in Drug Delivery

E. Mikayilov, D. Taghiyev, N. Zeynalov and S. Taghiyev

Abstract
Polyvinylpyrrolidone (PVP) is widely recognized for its hydrophilic properties, making it essential in pharmaceutical and biomedical industries as a carrier material. This review examines PVP-enriched delivery systems, emphasizing their capacity to integrate diverse active agents from both organic and synthetic sources. The versatility of PVP is showcased through its use in different formulations, such as microparticles, nanoparticles, fibrous structures, hydrogels, and tablets, which emphasize its potential in innovative drug delivery mechanisms. The review thoroughly examines the customized morphologies for specific PVP-drug combinations, detailing the active agents, methodologies, and processing parameters used. It discusses the advantages and challenges of these systems, underscoring the polymer’s significant role in novel pharmaceutical product development. Overall, this detailed analysis confirms PVP’s critical position in advancing drug delivery technologies, showcasing its multifaceted applications and potential for pioneering new treatments.

This work is licensed under a Creative Commons Attribution 4.0 International License

Keywords
nanoparticles, hydrogels, computational modeling, polyvinylpyrrolidone (PVP), drug delivery